St. Philomena School is an abandoned Catholic school in East Cleveland, Ohio.

On September 7, 2008, the Cleveland Catholic Diocese announced that it would begin implementing a downsizing plan that would close more than 45 churches in the region. 1 St. Philomena in East Cleveland and St. Louis and Christ the King in Cleveland Heights would merge with St. Ann in Cleveland Heights to form the Communion of Saints Parish. 2 St. Philomena would remain open for worship and outreach although its grade school would close by 2010.